一、个人情况基本介绍:
男,生于1974年7月,无党派人士,籍贯山东省滕州市。现为海南大学海洋学院药学系研究员,硕士研究生导师。
个人具体教育背景
博士后:2011年美国西北大学,生物医学工程系,指导教授; P. B. Messersmith
博士:2005年12月,美国西北大学,化学系,指导教授:J. B. Lambert
学士:1998年7月,中国科学技术大学,化学物理系,指导教授:吴奇院士
二、教学情况:药用有机化学,药用英语,和其它课程
三、科研情况:
博士期间,借鉴酶和氨基酸的结构特征,合成以Si为中心的可选择吸收气体的金属有机多孔材料。
博士毕业后,探索了儿茶酚胺的丙酮叉保护,可用于合 成重要中间体Fmoc-DOPA(Acetonide)-OH,在美国售价达 $400/g;设计合成了数种含儿茶酚的高分子材料被用于高端医学研究。在海南大学期间,主攻含多巴的多肽合成和抗帕金森病的药物研发。
总共发表了8篇学 术论文,都被SCI收录;国际会议论文6篇,其中1篇被ISTP收录。1篇影响因子14.829(被引用次数69);1篇影响因子13.734(被引用次 数50);1篇影响因子8.238(被引用次数20);2篇影响因子 4.145(被引用次数17,17)。有两项发明专利申请,都获得美国专利局授权(US8227628和US8293867).曾为 Biomacromolecules, J. Phys. Org. Chem., Crystal Growth & Design 等SCI杂志的审稿人。
四、近五年代表性研究项目及成果
科研项目
2016年,主持海南省自然科学基金一项(2016-2018年)
2014年, 主持国家自然科学基金项目一项(2015-2018年) ---新型抗帕金森病寡肽前药库的建立与筛选。
研究成果
2014年,美国专利US8829154B2 被批准并发表
2012年,美国专利US8227628B2 被批准并发表
2011年,
HO Ham, Zhongqiang Liu, KH Lau, H Lee, PB Messersmith. Facile DNA immobilization on surfaces through a catecholamine polymer, Angewandte Chemie, Intl. 123 (3), 758-762
KCL Black, Zhognqiang Liu, PB Messersmith. Catechol redox induced formation of metal core? polymer shell nanoparticlesChemistry of Materials 23 (5), 1130-1135
路延笃
Yandu LU
Ph. D, Professor
Group leader of Marine Environmental Microbiology
State Key Laboratory of Marine Resource Utilization in South China Sea
http://orcid.org/0000-0002-0136-2252
E-MAIL: ydlu[at]hainu.edu.cn
Research Experiences
2015-
Professor, Lead of Marine Environmental Microbiology Group
College of Oceanology, Hainan University
2012- 2015
Associated Professor, Lead of Metabolic Engineering Team, Single-Cell Center BioEnergy Genome Center, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences (CAS)
2010- 2012
Assistant Professor, Functional Genomics Group
BioEnergy Genome Center, Qingdao Institute of Bioenergy and Bioprocess Technology, CAS
Research Interests
I have been interested in the organization, evolution and function of eukaryotic genomes, in particular, photosynthetic microorganisms. My selected research experience includes: (1)
Genetic modify and characterize key metabolite evolution, biosynthesis and regulation in photosynthetic unicellular microalgae, e.g., Chlorella vulgaris NJ7, Haematococcus pluvialis, and Nannochloropsis oceanica (Lu et al 2015 Trends Plant Sci; Lu et al 2014 Plant J; Lu et al 2014 Biotech Biofuels; Lu et al 2010 Lipids; Lu et al 2009 Extremophiles; Lu et al 2010 Bioresource Technol); (2)
Design and optimize transformation strategies, develop mutagenesis library, multiple-gene co-expression system and CAS9 based targeted gene knockout technology for N. oceanica (Lu#, Xin#, unpublished; Wang#, Lu# et al 2016 Plant J; Lu et al 2009 J Integ Agr; Lu et al 2008 Plant Cell Rep); (3) Development of detection and customized approach for controlling microbial contamination in microalgal cultivation (Gan et al 2017 Adv Sci; Gan et al 2013 J Phytopathol; Gan et al Algal Res in revision).
Selected publications (#equal contributor; *correspondence)
1.Q Gan, X Wang, Y Wang, Z Xie, Y Tian, Y Lu*. (2017) Adv Sci. 10.1002/advs.201700127 (IF2017=9.0)
2.Q Gan#, W Zhou#, S Wang, X Li, Z Xie, J Wang, J Jiang, Y Lu* (2017) Algal Res in revision (IF2017=4.0)
3.L Wei, Q Wang, Y Xin, Y Lu, J Xu. (2017) Algal Res in press (IF2017=4.0)
4.Q Wang#, Y Lu#, Y Xin, L Wei, S Huang, J Xu. (2016) Plant J. DOI: 10.1111/tpj.13307 (IF2017=5.9)
5.Y Lu*, J Xu*. (2015) Trends Plant Sci. 20, 5, 273-282 (IF2017=11.9)
6.Y Lu, D Tarkowská, V Ture?ková, T Luo, Y Xin, J Li, Q Wang, N Jiao, M Strnad, J Xu. (2014) Plant J. 80, 1, 52–68 (IF2017=5.9)
7.Y Lu#, W Zhou#, L Wei, J Li, J Jia, F Li, S Smith, J Xu. (2014) Biotechnol Biofuels. 7:81 DOI: 10.1186/1754-6834-7-81 (IF2017=5.2)
8.Y Lu, P Jiang, S Liu, Q Gan, H Cui, S Qin. (2010) Bioresource Technol 101(16): 6468-6474 (IF2017=5.7)
9.D Wang#, Y Lu#, H Huang, J Xu. (2012) Adv Biochem Eng Biot DOI: 10.1007/10_2011_122 (IF2017=2.2)
10.Q Gan, Y Lu*, X Shao, T Sun, Y Li, C Liu. (2013) J Phytopathol. 162(3) 190–194 (IF2017=0.9)
11.Y Lu, X Chi, Z Li, Q Yang, S Liu, Q Gan, S Qin. (2010) Lipids 45(2): 179-187 (IF2017=1.9)
12.Y Lu#, X Chi#, Q Yang, Z Li, F Li, S Liu, Q Gan, S Qin. (2009) Extremophiles 13(7): 875-884 (IF2017=2.2)
13.Y Lu, Q Gan, X Chi, S Qin*. (2008) Plant Cell Rep 27(10): 1571-1579 (IF2017=2.9)
14.S Liu, Y Chen, Y Lu, H Chen, S Qin. (2010) Photosynth Res 105(2): 135-142 (IF2017=3.9)
15.P Cai, Q Huang, Y Lu, W Chen, D Jiang, W Liang. (2007) J Environ Sci 19(11): 1326-1329 (IF2017=2.9)
16.S Liu, H Chen, W Zhang, X Guan, F Li, Y Lu. (2009) Biochem Eng J 48(1): 58-64 (IF2017=2.9)
Grant
1.PI, 2018-20 Project of Innovation & Development of Marine Economy.
2.PI, 2018-19 Natural Science Foundation of Hainan Province.
3.Co-PI, 2018-19 Open Project of State Key Laboratory of Marine Resource Utilization in South China Sea.
4.PI, 2017-18 Funding of State Key Laboratory of Marine Resource Utilization in South China Sea.
5.PI, 2017-18 Innovation and Entrepreneurship Training Program for College Students, State Education Ministry.
6.PI, 2015-20 National Basic Capacity Improvement Project of Western and Central China.
7.PI, 2013-15 Basic Research in Science and Technology Plan Projects of Qingdao.
8.PI, 2013-15 Key Innovative Project of CAS.
9.Co-PI, 2013-15 National High-Tech Research and Development Plan of China.
10.PI, 2012-15 National Science Founding of China.
11.PI, 2010-11 Key Innovative Project of CAS.
Honors, Services and Fellowships
President Scholarship of CAS, 2010 (the highest honor for Ph. D students of CAS)
Pollyanna Chu Award for Outstanding Doctors of CAS, 2009
Serve as a review for a variety of journals including Algal Research, Journal of Applied Phycology, and Journal of Plant Growth Regulation.
Postdoc
G Ramanjaneyulu (2017)
Students
Jiang Jiaoyun, Li Falan, Xie Zineng, Lu Xiangning, Han Xiao, Cheng Ruoyang, Li Xianzhu, Zhang Zhicong, Yu Renhua, Zhang Huangsheng, Hou Congcong, Yang Chenhui, Tan Jian