作者： Tengfei Bian ^{#  1}, Yuzhi Wang ^{#  1}, Jordy F Botello  ¹, Qi Hu  ¹, Yunhan Jiang  ², Adriana Zingone  ³, Haocheng Ding  ⁴, Yougen Wu  ^{1   5}, F Zahra Aly  ⁶, Ramzi G Salloum  ⁷, Graham Warren  ⁸, Zhiguang Huo  ⁴, Bríd M Ryan  ³, Lingtao Jin  ², Chengguo Xing  ⁹ （Affiliations ¹ Department of Medicinal Chemistry, Center for Natural Products, Drug Discovery and Development (CNPD3), University of Florida, Gainesville, FL, 32610, USA. ² Department of Molecular Medicine, UT Health San Antonio, San Antonio, TX, 78229, USA. ³ Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA. ⁴ Department of Biostatistics, College of Public Health & Health Professions, College of Medicine, University of Florida, Gainesville, FL, 32610, USA. ⁵ College of Tropical Agriculture and Forestry, Hainan University, 58 Renmin Avenue, Haikou, 570228, China. ⁶ Department of Pathology, Immunology and Laboratory Medicine, University of Florida, 1345 Center Drive, Gainesville, FL, 32610, USA. ⁷ Department of Health Outcome & Biomedical Informatics, College of Medicine, University of Florida, Gainesville, FL, 32610, USA. ⁸ Department of Radiation Oncology, Medical University of South Carolina, Charleston, SC, 29425, USA. ⁹ Department of Medicinal Chemistry, Center for Natural Products, Drug Discovery and Development (CNPD3), University of Florida, Gainesville, FL, 32610, USA. chengguoxing@cop.ufl.edu.）

出处： Oncogene 2022

摘要： LKB1 loss of function is one key oncogenic event in lung cancer. Clinical data suggest that LKB1 loss of function is associated with patients' smoking ...

作者： Jiang-Shan Hao¹;Jiang-Shan Hao²;Jian-Feng Xing¹;Xu Hu¹;Zhi-Yong Wang³;Min-Qiang Tang³;Li Liao¹ （¹College of Tropical Crops, Hainan University, Haikou, China;²Jinhua Polytechnic, Jinhua, China;³Key Laboratory of Genetics and Germplasm Innovation of Tropical Special Forest Trees and Ornamental Plants, Ministry of Education, College of Forestry, Hainan University, Haikou, China）

出处： Frontiers in Plant Science 2022

关键词： Seashore paspalum;DNA 6mA modification;gene expression;stress resistance;transcription start site

摘要： N6-methyladenine (6mA) DNA modification has been detected in several eukaryotic organisms, in some of them, it plays important role in the regulation ...

作者： Teng Zhou¹CA1;Xiaohan He¹;Juncheng Zhao¹;Liuyong Shi¹;Liping Wen^1,2CA2 （¹Mechanical and Electrical Engineering College, Hainan University, Haikou 570228, China;²CAS Key Laboratory of Bio-inspired Materials and Interfacial Science, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, China）

出处： Chinese Chemical Letters 2022

关键词： Nanopore;Polyelectrolyte brush layer;Protonation and deprotonation reactions;Velocity;Ion current

摘要： Nanopore detection is a hot issue in current research. One of the challenges is how to slow down the transport velocity of nanoparticles in nanopores. ...

作者： Shuang-feng Dai¹;Xun-ge Zhu²;Ge-rang Hutang²;Jia-yue Li¹;Jia-qi Tian¹;Xian-hui Jiang¹;Dan Zhang³;Li-zhi Gao¹;Li-zhi Gao²;Li-zhi Gao³ （¹Institution of Genomics and Bioinformatics, South China Agricultural University, Guangzhou, China;²Plant Germplasm and Genomics Center, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China;³College of Tropical Crops, Hainan University, Haikou, China）

出处： Frontiers in Plant Science 2022

关键词： Oryza;genome size;flow cytometry;k-mer analysis;transposable elements

摘要： Genome size variation and evolutionary forces behind have been long pursued in flowering plants. The genus Oryza, consisting of approximately 25 wild ...

作者： Nianlong Han¹;Ke Hu²;Miao Yu²;Peihong Jia²;Yiqing Zhang³ （¹School of Geography and Tourism, Huizhou University, Huizhou 516007, China;²School of Public Administration, Hainan University, Haikou 570228, China;³School of Resource and Environmental Science, Wuhan University, Wuhan 430072, China）

出处： Applied Sciences 2022

关键词： ecological constraints;PLUS;urban growth boundary;tropical city

摘要： The rapid expansion of cities in tropical regions has triggered a series of problems such as the destruction of rare natural resources and decreases i ...

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作者： Guimei Wu¹;Aiyou Huang¹;Yanhong Wen²;Hongxia Wang³;Jiangxin Wang⁴;Fuguang Luo²;Mingcan Wu¹ （¹State Key Laboratory of Marine Resource Utilization in South China Sea, College of Oceanology, Hainan University, Haikou, China;²Liuzhou Aquaculture Technology Extending Station, Liuzhou, China;³Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China;⁴College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, China）

出处： Frontiers in Microbiology 2022

关键词： carbonate bioerosion;euendoliths;aquatic environment;Cyanobacteria;Proteobacteria;carbon sequestration

摘要： Shellfish, mussels, snails, and other aquatic animals, which assimilate limestone (calcium carbonate, CaCO3) to build shells and skeletons, are effect ...

作者： Gaobo Yu¹;Qiusen Chen¹;Fengqiong Chen²;Hanlin Liu¹;Jiaxin Lin¹;Runan Chen¹;Runan Chen³;Chunyuan Ren²;Jinpeng Wei²;Jinpeng Wei⁴;Yuxian Zhang²;Fengjun Yang¹;Yunyan Sheng¹ （¹College of Horticulture and Landscape Architecture, Heilongjiang Bayi Agricultural University, Daqing, China;²College of Agriculture, Heilongjiang Bayi Agricultural University, Daqing, China;³College of Tropical Crop, Hainan University, Haikou, China;⁴Ministry of Agriculture and Rural Affairs Agro-products and Processed Products Quality Supervision, Inspection and Testing Center, Daqing, China）

出处： Frontiers in Plant Science 2022

关键词： UDP-glycosyltransferase;tomato (Solanum lycopersicum);glutathione;chlorothalonil residues;gene expression

摘要： Reduced glutathione (GSH) is a key antioxidant, which plays a crucial role in the detoxification of xenobiotics in plants. In the present study, gluta ...

作者： Shouguo Yang^1,2,3,4;Xi Li^1,4;Zhan Zang¹;Jiaoni Li¹;Aimin Wang^1,2;Yaohua Shi²;Xingzhi Zhang^1,5;Zhifeng Gu^1,2;Xing Zheng^1,2CA1;Hebert Ely Vasquez^1,2CA2 （¹Department of Aquaculture, College of Marine Sciences, Hainan University, 58 Renmin Avenue, Haikou, Hainan 570228, PR China;²State Key Laboratory of Marine Resource Utilization in South China Sea (Hainan University), 58 Renmin Avenue, Haikou, Hainan 570228, PR China;³Hainan Academy of Ocean and Fisheries sciences, 12 Baiju Avenue, Haikou 571126, Hainan, PR China;⁴Co-first authors: these authors contributed equally to this work.;⁵Guangxi Academy of Fisheries Sciences, 8 Qingshan Road, Nanning 530021, Guangxi, PR China）

出处： Aquaculture Reports 2022

关键词： Pteria penguin;Microalgae substitution;Enzymatic activity;Gut microbiota

摘要： The effects of fresh and spray-dried microalgal diets on the growth, digestive enzymatic activity, and gut microbial community were investigated in ju ...

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作者： Dongli Lv¹;Jinmei Xia²;Xiaoqing Guan³;Qiliang Lai²;Beibei Zhang²;Jianhui Lin²;Zongze Shao²;Sulan Luo¹;Dongting Zhangsun¹;Jiang-Jiang Qin³;Weiyi Wang² （¹Key Laboratory of Tropical Biological Resources of Ministry of Education, School of Pharmaceutical Sciences, Hainan University, Haikou, China;²Key Laboratory of Marine Biogenetic Resources, Third Institute of Oceanography, Ministry of Natural Resources, Xiamen, China;³The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer, Chinese Academy of Sciences, Hangzhou, China）

出处： Frontiers in Microbiology 2022

关键词： Aspergillus;cytotoxic;antibacterial;NMR;indole diketopiperazine

摘要： Two new indole diketopiperazines (1–2) obtained from the fermentation culture of a deep-sea-derived fungus Aspergillus chevalieri MCCC M23426, were ch ...

作者： Chan Liu¹;Chan Liu²;Zhipei Sang³;Hong Pan¹;Hong Pan²;Qin Wu²;Yu Qiu¹;Jingshan Shi² （¹Department of Pharmacology and Chemical Biology, Shanghai Universities Collaborative Innovation Center for Translational Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai, China;²Key Laboratory of Basic Pharmacology of Ministry of Education, Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, China;³Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Hainan University, Haikou, China）

出处： Frontiers in Aging Neuroscience 2022

关键词： Alzheimer’s disease;multi-target-directed ligands;acetylcholinesterase;amyloid-β;neuroinflammation

摘要： BackgroundsAlzheimer’s disease (AD) is a multifactorial neurodegenerative disease. The treatment of AD through multiple pathological targets may gener ...